Phone : +8801712414074 || Email : support@oriopharma.com
Facebook Twitter Pinterest linkedin Telegram
  • CONTACT US
  • FAQs
Facebook Twitter Pinterest linkedin Telegram
Orio pharma Orio pharma
Select category
  • Select category
  • Bladder Cancer
  • Breast Cancer
  • Colorectal Cancer
  • Diabetic
  • Endometrial Cancer
  • Hepatitis B Virus
  • Hepatitis C Virus
  • Leukaemia
  • ONCOLOGY PRODUCTS
  • Rectal Cancer
  • Solid Tumor
  • Taskin
    • Anti-Diabetic
    • BEST SELLER
    • Bladder Cancer
    • Breast Cancer
    • Colon & Rectal Cancer
    • Colorectal Cancer
    • Diabetic
    • Endometrial Cancer
    • Hepatitis B Virus
    • Hepatitis C Virus
    • Ibrutinib
    • Kidney Cancer
    • Leukaemia
    • Liver Cancer
    • Lung Cancer
    • Lymphoma
    • Mantle Cell Lymphoma
    • Melanoma
    • Non-Hodgkin
    • ONCOLOGY
    • ONCOLOGY PRODUCTS
      • Ovarian Cancer
      • Pancreatic Cancer
      • Peritoneal Cancer
      • Primary Biliary Cirrhosis
      • Prostate Cancer
      • Renal Cell Carcinoma
      • Rheumatoid Arthritis
      • Thrombocytopenia
      • Thyroid Cancer
      • Tumors Cancer
  • Tumor
Login / Register
0 Wishlist
0 Compare
0 items / £0.00
Menu
Orio pharma Orio pharma
0 items / £0.00
Browse Categories
  • Anti-Diabetic
  • BEST SELLER
  • Bladder Cancer
  • Breast Cancer
  • Colon & Rectal Cancer
  • Colorectal Cancer
  • Diabetic
  • Endometrial Cancer
  • Hepatitis B Virus
  • Hepatitis C Virus
  • Ibrutinib
  • Kidney Cancer
  • Leukaemia
  • Liver Cancer
  • Lung Cancer
  • Lymphoma
  • Mantle Cell Lymphoma
  • Melanoma
  • Non-Hodgkin
  • ONCOLOGY
  • ONCOLOGY PRODUCTS
  • Ovarian Cancer
  • Pancreatic Cancer
  • Peritoneal Cancer
  • Primary Biliary Cirrhosis
  • Prostate Cancer
  • Renal Cell Carcinoma
  • Rheumatoid Arthritis
  • Thrombocytopenia
  • Thyroid Cancer
  • Tumors Cancer
  • Home
  • ONCOLOGY PRODUCTS
  • UPLOAD PRESCRIPTION
MEZOXIA
Click to enlarge
HomeShopTaskinONCOLOGY PRODUCTSPeritoneal Cancer MEZOXIA 160 MG
Previous product
MAXWEL
Back to products
Next product
NEXANIB
NEXANIB 200 MG

MEZOXIA 160 MG

Compare
Add to wishlist
Categories: BEST SELLER, Bladder Cancer, Bladder Cancer, Colon & Rectal Cancer, Colorectal Cancer, Diabetic, Endometrial Cancer, Hepatitis B Virus, Hepatitis C Virus, Ibrutinib, Leukaemia, Lung Cancer, ONCOLOGY PRODUCTS, Peritoneal Cancer, Primary Biliary Cirrhosis, Prostate Cancer, Thrombocytopenia, Thyroid Cancer Tags: Bangladesh Mdedicine, Cancer, Cancer Capsule, Cancer Chemotherapy, Cancer Drug, Cancer Therapy, Chemotherapy, Chemotherapy in Bangladesh, Chemotherapy Tablets, Everest Pharmaceuticals Ltd., Hormonal Chemotherapy, Medicine In Bangladesh, Megestrol Acetate, MEZOXIA, MEZOXIA 160 MG, Mezoxia Tablet
Share
Facebook Twitter Pinterest linkedin Telegram
  • Description
  • Reviews (0)
  • Shipping & Delivery
Description

Tablet Mezoxia Tablet

Megestrol Acetate
160 mg
Everest Pharmaceuticals Ltd.

Indications

Megestrol Acetate is indicated for the palliative treatment of advanced carcinoma of the breast or endometrium (i.e., recurrent, inoperable, or metastatic disease). It should not be used instead of currently accepted procedures such as surgery, radiation, or chemotherapy.

Therapeutic Class

Hormonal Chemotherapy

Pharmacology

Megestrol Acetate is a synthetic, antineoplastic and progestational drug. While the precise mechanism by which Megestrol Acetate produces its antineoplastic effects against endometrial carcinoma is unknown at the present time, inhibition of pituitary gonadotrophin production and resultant decrease in estrogen secretion may be factors. The antineoplastic action of megestrol acetate on carcinoma of the breast is effected by modifying the action of other steroid hormones and by exerting a direct cytotoxic effect on tumor cells. In metastatic cancer, hormone receptors may be present in some tissues but not others. The receptor mechanism is a cyclic process whereby estrogen produced by the ovaries enters the target cell, forms a complex with cytoplasmic receptor and is transported into the cell nucleus. There it induces gene transcription and leads to the alteration of normal cell functions. Pharmacologic doses of megestrol acetate not only decrease the number of hormone-dependent human breast cancer cells but also are capable of modifying and abolishing the stimulatory effects of estrogen on these cells.

Estimates of plasma levels of Megestrol Acetate are dependent on the measurement method used. Peak plasma concentrations occur 2 to 3 hours after a single oral dose 160 mg tablets. The plasma half-life of Megestrol Acetate is 33 to 38 hours. Approximately 66% of an administered dose is excreted in the urine and approximately 20% in the faeces.

Dosage & Administration

  • Breast cancer: 160 mg/day
  • Endometrial carcinoma: 40-320 mg/day in divided doses.
  • At least 2 months of continuous treatment is considered an adequate period for determining the efficacy of Megestrol.

Interaction

Pharmacokinetic studies show that there are no significant alterations in pharmacokinetics parameters of Zidovudine or Rifabutin to warrant dosage adjustment when Megestrol Acetate is administered with these drugs. The effects of Zidovudine or Rifabutin on the pharmacokinetics of Megestrol Acetate were not studied.

Contraindications

History of hypersensitivity to Megestrol Acetate or any component of the formulation. Known or suspected pregnancy.

Side Effects

Weight Gain: Weight gain is a frequent side effect of Megestrol Acetate. This gain has been associated with increased appetite and is not necessarily associated with fluid retention.

Thromboembolic Phenomena: Thromboembolic phenomena including thrombophlebitis and pulmonary embolism (in some cases fatal) have been reported.

Glucocorticoid Effects: The glucocorticoid activity of Megestrol Acetate has not been fully evaluated. Clinical cases of new onset diabetes mellitus, exacerbation of preexisting diabetes mellitus, and overt Cushing’s syndrome have been reported in association with the chronic use of Megestrol Acetate. In addition, clinical cases of adrenal insufficiency have been observed in patients receiving or being withdrawn from chronic Megestrol Acetate therapy in the stressed and non-stressed state.

Other: Nausea, dyspnea, tumor flare, hyperglycemia, glucose intolerance, alopecia, hypertension, carpal tunnel syndrome, mood changes, hot flashes, malaise, asthenia, lethargy, sweating and rash.

Pregnancy & Lactation

Pregnancy Category D. The use of progestational agents during the first four months of pregnancy is not recommended. Very small amounts (approximately 0.1%) are excreted in mother’s milk. It is however, not known whether these amounts exert any harmful effect on the newborn. Because of the potential for adverse effects on the new born, nursing should be discontinued during treatment with Megestrol Acetate.

Precautions & Warnings

General: Close surveillance is indicated for any patient treated for recurrent or metastatic cancer. Use with caution in patients with a history of thromboembolic disease.

Use in Diabetics: Exacerbation of preexisting diabetes with increased insulin requirements has been reported in association with the use of Megestrol Acetate.

Use in Special Populations

Pediatric Use: Safety and effectiveness in pediatric patients have not been established.

Geriatric Use: In the dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal or cardiac function, and of concomitant disease or other drug therapy.

Overdose Effects

No serious unexpected side effects have resulted from studies involving Megestrol Acetate administered in dosages as high as 1600 mg/day.

Storage Conditions

Store at or below 25°C. Protect from heat, light & moisture.
Reviews (0)

Reviews

There are no reviews yet.

Be the first to review “MEZOXIA 160 MG” Cancel reply

Your email address will not be published. Required fields are marked *

Shipping & Delivery

Related products

CRIZOCENT
Compare
Close

CRIZOCENT 250 MG

Presentation Crizocent 250: Each capsule contains Crizotinib INN 250 mg Description Crizotinib is an inhibitor of receptor tyrosine kinases including
Add to wishlist
Read more
Quick view
ELOPAG
Compare
Close

ELOPAG 25 MG

 Elopag Tablet Eltrombopag Olamine 25 mg Everest Pharmaceuticals Ltd. Indications Eltrombopag Olamine is indicated in Chronic Immune (Idiopathic) Thrombocytopenia, Chronic Hepatitis
Add to wishlist
Read more
Quick view
ELOPAG
Compare
Close

ELOPAG 50 MG

 Elopag Tablet Eltrombopag Olamine 50 mg Everest Pharmaceuticals Ltd. Also available as: 25 mg Indications Eltrombopag Olamine is indicated in Chronic
Add to wishlist
Read more
Quick view
Placeholder
Compare
Close

LYNIB 100 MG

Lynib medicine 100mg Olaparib treats Ovarian cancer Brand name: Lynib Active ingredient: Olparib Content: 100mg Form: Capsules Package: 1 box of
Add to wishlist
Read more
Quick view
LARONIB
Compare
Close

LARONIB 100 MG

DESCRIPTION Laronib Larotrectinib 25 mg & 100 mg COMPOSITION LARONIB 25 capsules: Each capsule contains Larotrectinib Sulfate INN equivalent to
Add to wishlist
Read more
Quick view
ACLOPAIN
Compare
Close

ACLOPAIN 100 MG

Indications Aceclofenac is indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, toothache, trauma and
Add to wishlist
Read more
Quick view
HEPANIB
Compare
Close

HEPANIB 200 MG

 Hepanib Tablet Sorafenib Tosylate 200 mg Everest Pharmaceuticals Ltd. Indications Hepatocellular Carcinoma: Sorafenib is indicated for the treatment of patients with
Add to wishlist
Read more
Quick view
IBRUXEN
Compare
Close

IBRUXEN 140 MG

 Ibruxen Capsule Ibrutinib 140 mg Everest Pharmaceuticals Ltd. Indications Mantle Cell Lymphoma: Ibrutinib is indicated for the treatment of patients with
Add to wishlist
Read more
Quick view
Vitra
Magisso
Louis Poulsen
KLÖBER
Joseph Joseph
Hay
Flos
Eva Solo
Alessi

OrioPharma is one of the leading and most reputed finished pharmaceutical products suppliers in Bangladesh.

48/A-B, Baitul Khair, Level-9, Purana Paltan,Dhaka-1000
Phone: +8801712414074
Whatsapp & WeChat: +8801712414074
Recent Posts
  • ASA_apnea_side_effects
    Elopag 50 side effects
    October 19, 2021 No Comments
  • osicent-80mg-30s-500x500-500x500-1
    Osicent 80 Uses
    October 19, 2021 No Comments
ONCOLOGY
  • Bladder Cancer
  • Breast Cancer
  • Colorectal Cancer
  • Endometrial Cancer
  • Hepatitis B Virus
  • Hepatitis C Virus
ONCOLOGY
  • Bladder Cancer
  • Breast Cancer
  • Colorectal Cancer
  • Endometrial Cancer
  • Hepatitis B Virus
  • Hepatitis C Virus
Company
  • Terms and Conditions
  • Privacy Policies
  • UPLOAD PRESCRIPTION
  • Contact Us
www.oriopharma.com 2021 CREATED BY -SHUKHI IT
payments

Shopping cart

close
  • Menu
  • Categories
  • Anti-Diabetic
  • BEST SELLER
  • Bladder Cancer
  • Breast Cancer
  • Colon & Rectal Cancer
  • Colorectal Cancer
  • Diabetic
  • Endometrial Cancer
  • Hepatitis B Virus
  • Hepatitis C Virus
  • Ibrutinib
  • Kidney Cancer
  • Leukaemia
  • Liver Cancer
  • Lung Cancer
  • Lymphoma
  • Mantle Cell Lymphoma
  • Melanoma
  • Non-Hodgkin
  • ONCOLOGY
  • ONCOLOGY PRODUCTS
  • Ovarian Cancer
  • Pancreatic Cancer
  • Peritoneal Cancer
  • Primary Biliary Cirrhosis
  • Prostate Cancer
  • Renal Cell Carcinoma
  • Rheumatoid Arthritis
  • Thrombocytopenia
  • Thyroid Cancer
  • Tumors Cancer
  • Home
  • ONCOLOGY PRODUCTS
  • UPLOAD PRESCRIPTION
  • Wishlist
  • Compare
  • Login / Register

Sign in

close

Lost your password?
No account yet? Create an Account
Scroll To Top