Lorbrexen 100 mg (Lorlatinib) Tablets


Lorbrexen 100 mg (Lorlatinib) Tablets


Lorbrexen 100 mg, a groundbreaking creation by Everest Pharmaceuticals Ltd. and distributed by Orio Pharma, stands at the forefront of advanced lung cancer treatment. Lorlatinib, the active ingredient in Lorbrexen, signifies a significant advancement in precision medicine, offering hope to individuals facing the challenges of advanced lung cancer. This medication not only embodies cutting-edge innovation in manufacturing by Everest Pharmaceuticals Ltd. but also ensures widespread accessibility through the dedicated distribution efforts of Orio Pharma.

Description: Lorbrexen 100 mg encapsulates the potent properties of Lorlatinib, a third-generation tyrosine kinase inhibitor celebrated for its ability to target specific genetic mutations associated with non-small cell lung cancer (NSCLC).

Mechanism of Action: Lorlatinib, the cornerstone of Lorbrexen, inhibits specific tyrosine kinases, including ALK and ROS1, which play a crucial role in the growth and survival of cancer cells. By targeting these specific mutations, Lorbrexen provides a highly targeted and effective intervention against advanced NSCLC.

Clinical Use:

Lorbrexen 100 mg is primarily prescribed for:

  • ALK-Positive NSCLC: Lorbrexen is a first-line treatment for patients with ALK-positive NSCLC, particularly those who have progressed on or are intolerant to previous ALK inhibitors.
  • ROS1-Positive NSCLC: Lorbrexen is also indicated for treating ROS1-positive NSCLC, demonstrating its versatility in addressing different genetic mutations.


Dosage and Administration: The dosage of Lorbrexen 100 mg is determined by healthcare professionals based on the specific genetic mutations present in the patient’s cancer and their characteristics. Administered orally, the treatment plan is tailored to optimize efficacy while minimizing potential side effects.

Benefits of Lorbrexen 100 mg:

  • Targeted Genetic Inhibition: Lorbrexen’s precision targeting of ALK and ROS1 mutations offers a highly effective intervention against the specific genetic drivers of NSCLC.
  • Extended Progression-Free Survival: Lorlatinib has demonstrated significant improvements in progression-free survival, providing patients with an extended duration of disease control.
  • Central Nervous System Efficacy: Lorbrexen exhibits remarkable efficacy in addressing brain metastases, a common complication in advanced NSCLC.

Manufacture Section: Manufacturer: Everest Pharmaceuticals Ltd.

Everest Pharmaceuticals Ltd., the esteemed manufacturer of Lorbrexen 100 mg, is dedicated to producing pharmaceuticals of the highest quality. With a commitment to innovation and adherence to stringent standards, Everest Pharmaceuticals Ltd. plays a pivotal role in advancing lung cancer treatment.

Supplier Section: Supplier: Orio Pharma

As the dedicated distributor of Lorbrexen 100 mg, Orio Pharma plays a vital role in ensuring the widespread accessibility of this crucial medication. Committed to excellence in supply chain management, Orio Pharma facilitates seamless access to Lorbrexen for healthcare providers and patients alike.

Conclusion: In conclusion, Lorbrexen 100 mg (Lorlatinib) represents hope in the complex landscape of advanced lung cancer treatment. Manufactured by Everest Pharmaceuticals Ltd. and supplied by Orio Pharma, this medication signifies more than just a treatment; it embodies a transformative tool in the fight against NSCLC.

The precision of Lorlatinib in targeting specific genetic mutations underscores its role as a potent and well-tolerated therapeutic option. The collaboration between Everest Pharmaceuticals Ltd. and Orio Pharma ensures not only the highest standards of manufacturing but also widespread accessibility for those in need. As the field of oncology continues to evolve, Lorbrexen 100 mg exemplifies the progress being made in providing more effective, personalized, and compassionate care for individuals facing the challenges of advanced lung cancer.