Hopso-VL (Sofosbuvir+ Velpatasvir 400mg + 100mg)


Hopso-VL (Sofosbuvir+ Velpatasvir 400mg + 100mg)

Introduction to Hopso-VL (Sofosbuvir + Velpatasvir )

Hopso-VL (Sofosbuvir + Velpatasvir ), meticulously manufactured by Drug International Ltd and distributed by Orio Pharma, represents a significant advancement in the treatment of Hepatitis C. This fixed-dose combination medication leverages the power of Sofosbuvir and Velpatasvir, providing a potent, once-daily oral treatment that addresses all major genotypes of Hepatitis C virus (HCV).

Description: Hopso-VL (Sofosbuvir + Velpatasvir )

Hopso-VL combines Sofosbuvir, a nucleotide analog inhibitor of HCV NS5B polymerase, and Velpatasvir, an HCV NS5A inhibitor. This dual-action formulation is designed to interfere with two critical steps in the HCV lifecycle, providing a comprehensive approach to eradicate the virus.

Mechanism of Action

Sofosbuvir inhibits the RNA-dependent RNA polymerase in HCV, which is essential for viral replication. Velpatasvir inhibits the HCV NS5A protein, which plays a key role in viral RNA replication and virion assembly. By targeting these two separate mechanisms, Hopso-VL effectively prevents the virus from multiplying and spreading, leading to viral eradication.

Clinical Use

Hopso-VL 400mg + 100mg is primarily prescribed for:

  • Hepatitis C Virus (HCV) Infection: Indicated for the treatment of chronic HCV infection in adults, covering all major genotypes (1-6).

Dosage and Administration

The recommended dosage of Hopso-VL is one tablet taken orally once daily with or without food. The treatment duration typically spans 12 weeks, depending on the patient’s condition and treatment response. Healthcare professionals determine the specific regimen based on individual patient factors and HCV genotype.

Benefits of Hopso-VL (Sofosbuvir + Velpatasvir )

  • Pan-genotypic Efficacy: Effective across all HCV genotypes (1-6), offering a universal treatment solution.
  • High Cure Rates: Demonstrates high sustained virologic response (SVR) rates, leading to a high likelihood of complete viral eradication.
  • Convenient Dosage: The once-daily oral tablet improves patient compliance and convenience.
  • Well-Tolerated: Generally well-tolerated with a favorable side effect profile, making it suitable for a broad range of patients.

Manufacturer: Drug International Ltd.

Drug International Ltd., the esteemed manufacturer of Hopso-VL, is dedicated to producing pharmaceuticals of the highest quality. With a strong commitment to innovation and adherence to stringent quality control standards, Drug International Ltd. plays a pivotal role in advancing the treatment of infectious diseases.

Supplier: Orio Pharma

Orio Pharma, the dedicated distributor of Hopso-VL, ensures the widespread accessibility of this vital medication. Committed to excellence in supply chain management, Orio Pharma facilitates seamless access to Hopso-VL for healthcare providers and patients globally.


In conclusion, Hopso-VL (Sofosbuvir + Velpatasvir ) stands as a significant advancement in the treatment of chronic Hepatitis C. Manufactured by Drug International Ltd. and supplied by Orio Pharma, this medication represents a comprehensive, effective, and convenient solution for patients across all HCV genotypes.

The dual-action mechanism of Sofosbuvir and Velpatasvir in inhibiting key steps in the HCV lifecycle underscores its role as a potent and well-tolerated therapeutic option. The collaboration between Drug International Ltd. and Orio Pharma ensures not only the highest standards of manufacturing but also widespread accessibility for those in need. As the field of infectious diseases continues to evolve, Hopso-VL exemplifies the progress being made in providing more effective, personalized, and compassionate care for individuals battling Hepatitis C.