Elopag 50 Mg (Eltrombopag) Tablet


Elopag 50 Mg (Eltrombopag) Tablet

Elopag 50 mg: Pioneering Hematological Care with Eltrombopag Olamine

Elopag, an innovative tablet containing Elopag 50 mg, represents a significant stride in the field of hematological therapy. This medication is expertly manufactured by Everest Pharmaceuticals Ltd., and it is designed to address various hematological conditions, including Chronic Immune (Idiopathic) Thrombocytopenia, Chronic Hepatitis C-associated Thrombocytopenia, and Severe Aplastic Anemia. Elopag brings renewed hope and therapeutic relief to patients grappling with these complex and challenging disorders.

Understanding Elopag: Elopag’s therapeutic prowess stems from its active component, Eltrombopag Olamine. This orally bioavailable, small-molecule TPO-receptor agonist engages with the transmembrane domain of the human TPO-receptor, thereby stimulating the phosphorylation of STAT and JAK. One remarkable aspect of Eltrombopag Olamine is its distinctive mode of action—it doesn’t activate the AKT pathway. Elopag’s introduction into the realm of hematological care has given rise to improved platelet counts, breathing new life into patients facing these hematological challenges.

Indications and Usage:

  1. Chronic Immune (Idiopathic) Thrombocytopenia: Elopag is an invaluable treatment for adult and pediatric patients aged 6 years and older diagnosed with ITP. The typical recommended dose for most patients is 50 mg, taken once daily. However, the importance of individual patient factors, such as hepatic impairment and East Asian ancestry, may necessitate a reduced dose.
  2. Chronic Hepatitis C-associated Thrombocytopenia: For patients dealing with this condition, the standard dosage is 25 mg once daily. Elopag plays a pivotal role in achieving the target platelet count required to initiate antiviral therapy.
  3. Severe Aplastic Anemia: In cases of severe aplastic anemia, Elopag is typically prescribed at an initial dose of 50 mg once daily. As in other scenarios, certain patient considerations may result in a reduced 25 mg daily dose.

Dose Modifications: Elopag offers the flexibility of dosing adjustments to cater to individual patient needs. Dose modifications or interruptions may become necessary for managing hematological and non-hematological toxicities. Rigorous monitoring and potential adjustments are essential to ensure that patients receive the most effective and safe treatment.

Safety and Efficacy: Elopag’s safety and efficacy have been rigorously evaluated across diverse patient populations. It’s essential to emphasize that pediatric patients, geriatric individuals, and those with hepatic or renal impairments may require specific dosage adjustments. Nevertheless, Elopag remains a vital tool in effectively managing hematological conditions.

Precautions and Warnings:

  • Hepatotoxicity: Continuous monitoring of liver function is of paramount importance during Elopag therapy.
  • Thrombotic or Thromboembolic Complications: Patients must be closely monitored for potential complications, including portal vein thrombosis.
  • Use in Special Populations: The safety and efficacy of Elopag have been scrutinized in various patient groups, leading to specific recommendations for pediatric, geriatric, and individuals with hepatic or renal impairments.

Overdose Effects: In cases of overdose, patients may experience excessive increases in platelet counts, potentially leading to thrombotic/thromboembolic complications. Adequate monitoring and, in some instances, the use of chelating agents are necessary to manage an overdose effectively.

Storage Conditions: Elopag should be stored in a cool and dry place, away from light and moisture, and kept out of the reach of children.

Affordable Access Worldwide: Orio Pharma, a reputable provider of oncology medicines in Bangladesh, is steadfast in its commitment to making Elopag 50 mg accessible at the most affordable prices worldwide. This dedication ensures that patients, regardless of their geographic location, can access this groundbreaking treatment without the burden of exorbitant costs. Orio Pharma stands at the forefront of delivering quality healthcare, backed by products from reputable manufacturers, thus providing reliable services to patients and healthcare professionals worldwide.

In conclusion, Elopag 50 mg, fortified with Eltrombopag Olamine, represents a significant leap in hematological care. With its innovative mechanism of action and flexible dosing options, it offers a promising solution to patients contending with conditions such as Chronic Immune (Idiopathic) Thrombocytopenia, Chronic Hepatitis C-associated Thrombocytopenia, and Severe Aplastic Anemia. Elopag 50 mg embodies Orio Pharma’s commitment to advancing healthcare on a global scale, bringing renewed hope and therapeutic relief to patients in need.