Azarest 300 mg (Azactidine)


Azarest 300 mg (Azactidine)

Introduction to Azarest 300 mg (Azacitidine)

Azarest 300 mg, meticulously formulated by Everest Pharmaceuticals Ltd. and supplied by Orio Pharma, represents a significant advancement in the treatment of myelodysplastic syndromes (MDS). Azacitidine, the active ingredient in Azarest, offers a targeted approach, providing hope and improved outcomes for individuals facing these complex blood disorders.

Description: Azarest 300 mg (Azacitidine)

Azarest 300 mg contains Azacitidine, an antineoplastic agent that works by promoting the restoration of normal growth and maturation of bone marrow cells. This medication inhibits DNA methylation, thereby reactivating tumor suppressor genes and inducing cellular differentiation and apoptosis.

Mechanism of Action

Azacitidine works by:

  • Inhibiting DNA methyltransferase, leading to hypomethylation of DNA.
  • Reactivating genes involved in cell differentiation and apoptosis.
  • Reducing the proliferation of abnormal bone marrow cells.

This comprehensive approach helps in managing myelodysplastic syndromes by addressing the underlying cellular abnormalities.

Clinical Use

Azarest 300 mg is primarily prescribed for:

  • Myelodysplastic Syndromes (MDS): Used to treat various types of MDS, improving blood counts and reducing the risk of progression to acute myeloid leukemia (AML).

Dosage and Administration

Healthcare professionals determine the dosage of Azarest 300 mg based on the specific type of MDS being treated and the individual patient’s response. Administered via subcutaneous injection or intravenous infusion, the treatment follows a specific schedule over a series of cycles. It is crucial to follow the prescribed regimen to achieve optimal results.

Benefits of Azarest 300 mg (Azacitidine)

  • Improved Blood Counts: Azarest helps improve red blood cell, white blood cell, and platelet counts.
  • Disease Progression Delay: Reduces the risk of progression to acute myeloid leukemia.
  • Enhanced Quality of Life: Supports better overall health and quality of life for patients with MDS.

Manufacturer: Everest Pharmaceuticals Ltd.

Everest Pharmaceuticals Ltd., the esteemed manufacturer of Azarest 300 mg, is dedicated to producing high-quality medications. Their commitment to innovation and stringent quality control ensures that Azarest meets the highest standards of efficacy and safety.

Supplier: Orio Pharma

Orio Pharma, the trusted supplier of Azarest 300 mg, ensures that this essential medication is accessible to healthcare providers and patients worldwide. Their dedication to excellence in distribution guarantees timely and reliable access to Azarest.


In conclusion, Azarest 300 mg (Azacitidine) is a groundbreaking medication for the treatment of myelodysplastic syndromes. Manufactured by Everest Pharmaceuticals Ltd. and supplied by Orio Pharma, this treatment offers a targeted and effective approach to managing MDS.

The action of Azacitidine in restoring normal cell growth and preventing disease progression underscores its role as a potent and well-tolerated therapeutic option. The collaboration between Everest Pharmaceuticals Ltd. and Orio Pharma ensures the highest standards of manufacturing and distribution, making Azarest 300 mg a reliable and accessible option for patients striving for better health outcomes in their battle against myelodysplastic syndromes.