Introduction

Dasatab 100 mg contains the active ingredient Dasatinib, a powerful tyrosine kinase inhibitor (TKI) used in the treatment of chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL).
Manufactured by Eskayef Pharmaceuticals Ltd. — one of Bangladesh’s leading pharmaceutical companies — Dasatab 100 mg is recognized globally for its high quality and effectiveness.

Supplied by Orio Pharma, a trusted name in oncology medicine distribution, Dasatab 100 mg ensures cancer patients worldwide have timely access to life-saving therapy.

About the Manufacturer: Eskayef Pharmaceuticals Ltd.

Founded in 1990, Eskayef Pharmaceuticals Ltd. (SK+F) is a renowned pharmaceutical manufacturer based in Bangladesh. Originally the Bangladesh operations of SK&F, USA, Eskayef was acquired by the Transcom Group, one of the country’s most reputed conglomerates.
For over 31 years, Eskayef has built a strong reputation for producing world-class medicines that meet stringent international standards.

Their unwavering commitment to quality, innovation, and excellence has made Eskayef a trusted name not only in Bangladesh but across the world.

Learn more about Eskayef here: www.skfbd.com

About the Supplier: Orio Pharma

Orio Pharma specializes in supplying high-quality anti-cancer and oncology medicines. Established in June 2019, Orio Pharma focuses on delivering reliable, essential medications to healthcare providers and patients worldwide, with guaranteed delivery within 3 to 7 working days.

Driven by values of compassion, integrity, innovation, and collaboration, Orio Pharma ensures that every product meets strict regulatory and quality standards.

Discover more about Orio Pharma: www.oriopharma.com

What is Dasatab 100 mg (Dasatinib)?

Dasatab 100 mg is an oral cancer treatment that inhibits abnormal tyrosine kinases like BCR-ABL, which are responsible for the uncontrolled growth of leukemia cells.
It is a targeted therapy — designed to stop cancer cells without harming normal cells — offering better outcomes compared to traditional chemotherapy.

Key Features of Dasatab 100 mg

• Active Ingredient: Dasatinib
• Strength: 100 mg per tablet
• Dosage Form: Oral Tablet
• Indications:
  • Chronic Myeloid Leukemia (CML)
  • Philadelphia chromosome-positive Acute Lymphoblastic Leukemia (Ph+ ALL)

Dasatab 100 mg offers once-daily dosing, making it convenient for patients undergoing long-term cancer treatment.

Mechanism of Action

Dasatinib blocks several kinases involved in cancer cell proliferation, especially BCR-ABL. By doing so, it stops the abnormal signaling that causes leukemia cells to multiply.
This leads to the apoptosis (natural death) of cancerous cells and slows disease progression.

Uses of Dasatab 100 mg

• Newly diagnosed chronic phase CML patients
• Patients resistant or intolerant to prior therapies (e.g., Imatinib)
• Accelerated phase or blast crisis CML
• Philadelphia chromosome-positive ALL (Ph+ ALL)

It is often considered a first-line or second-line treatment in global clinical practice.

Dosage and Administration

Recommended Dosage:

• Chronic Phase CML: 100 mg orally once daily
• Accelerated Phase/Blast Phase CML or Ph+ ALL: 140 mg daily (split doses possible)

Administration Tips:

• Take the tablet whole, with or without food.
• Avoid using antacids within 2 hours before or after dosing.
• Always follow your physician’s dosing schedule exactly.

If side effects occur, dosage modifications or interruptions may be necessary under medical supervision.

Common Side Effects

While Dasatab 100 mg is highly effective, patients may experience side effects such as:

• Fluid retention (pleural effusion, edema)
• Low blood counts (anemia, neutropenia)
• Gastrointestinal issues (diarrhea, nausea)
• Fatigue and skin rashes

Serious Risks Include:

• Pulmonary arterial hypertension (PAH)
• Bleeding disorders
• Cardiac abnormalities (QT interval prolongation)

Regular monitoring with blood tests and ECGs is recommended during therapy.

Precautions and Warnings

Before starting Dasatab 100 mg, inform your healthcare provider if you:

• Have heart, liver, or kidney issues
• Are pregnant, planning pregnancy, or breastfeeding
• Have a history of bleeding disorders

Pregnancy Warning: Dasatinib can cause fetal harm. Women of reproductive age should use effective contraception.

Drug Interactions

Dasatab 100 mg may interact with:

• CYP3A4 inhibitors/inducers (e.g., ketoconazole, rifampin)
• Proton pump inhibitors (e.g., omeprazole)
• Blood thinners (e.g., warfarin, aspirin)

Consult your doctor about any medicines you are taking.

Storage Instructions

• Store at 20°C to 25°C (68°F to 77°F).
• Protect from light, moisture, and heat.
• Keep out of children’s reach.

Why Choose Dasatab 100 mg from Orio Pharma?

• Authentic sourcing from Eskayef Pharmaceuticals Ltd.
• Rapid worldwide delivery within 3 to 7 working days
• Competitive pricing for global markets
• Support with regulatory and documentation requirements

With Orio Pharma, you can trust that you’re receiving the highest quality Dasatab 100 mg tablets to support your cancer treatment journey.

Frequently Asked Questions (FAQs)

Q1: Can I stop taking Dasatab 100 mg once I achieve remission?
A: Treatment duration should be determined by your oncologist. Never stop medication without medical advice.

Q2: How quickly does Dasatab 100 mg start working?
A: Some patients notice improvements in blood counts within weeks, but full cytogenetic or molecular responses may take months.

Q3: Is Dasatab 100 mg covered by insurance?
A: Coverage depends on your location and insurance plan. Contact your provider for details.

Q4: Can Dasatab be used in pediatric patients?
A: Its use in children requires special dosing and careful supervision by pediatric oncology specialists.

Conclusion

Dasatab 100 mg (Dasatinib), manufactured by Eskayef Pharmaceuticals Ltd. and supplied globally by Orio Pharma, represents a critical advancement in the treatment of CML and Ph+ ALL.
Its targeted action, proven efficacy, and high-quality manufacturing standards make it a preferred option for patients and healthcare providers worldwide.

Choose Orio Pharma — your trusted partner in oncology care — for safe, timely, and authentic access to Dasatab 100 mg.